1. Assign permissions to all items separated from list permission settings. There are times when you need to control permissions to all items but not want to inherit permissions from parent list permission settings. SharePoint Permission Boost Workflow can solve this problem instead of manually setting permissions to each item. With it, permission settings will be automatically applied to each item when this item is created or modified; 2. Assign ITEM-RELATED users or groups permissions to each item. For instance, in a task list, you want the assignee of one task, but not some specified users or groups, to have read permission to this task. Since each task item has its own assignee, it will be difficult if you set read permission to each item when assignee is appointed or changed. SharePoint Permission Boost Workflow brings in a concept named "TEM-RELATED users or groups" which actually means user or group columns in a list, to solve this problem. 3. Assign users or groups read/edit permissions to list columns. SharePoint does not define column permissions by default, but SharePoint Permission Boost controls column permissions by overwriting some control templates.